3D Recombinant  Protein Hydrogel

Unveil next-generation therapeutics through advance in biomaterials 

 

 

LitGel   Hydrogel for 3D Cell Culture

TM

LitGel   Hydrogel for 3D Cell Culture

TM

LitGel   is a photoresponsive protein hydrogel, which enables fast cell encapsulation and cell recovery at room temperature and pressure. It starts gelation at dark and exhibits a rapid gel-sol transition under light exposure. Unlike other hydrogels extracted from the ECM of animal cells, LitGel   is a genetically engineered elastin-like protein hydrogel without animal origins. It highly mimics in vivo environments similar to those tissues by supporting cell adhesion and migration.   

TM

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Features & Benefits

  • Biocompatible to a multitude of  cells (3T3 fibroblasts, mesenchymal stem cells, neurons, cancer cells, Jurkat, macrophage etc.)​​

 

  • Simple, easy to use, no harm to cells

  • Transparent for cell observation 

  • Customizable in viscoelasticity and bioactivities

 

How does it work?

LitGel consists of three main components: two elastin-based engineered proteins and biocompatible gelator. It is formed by self-assembly of the protein polymers through mixing them together. 

  • Elastin-based polymer A

 

  • Elastin-based polymer B

 

  • Gelation solution works at room temperature in the dark

 

  • Cell interactive components (e.g. RGD) & some cytokines (LIF) could be added

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Our Innovative Technology

LitGel is created by our proprietary recombinant protein hydrogel technology, which allows customization on the viscoelasticity and bioactivities and thus, we could develop a board pipeline of hydrogel products specific to research applications. The design and fabrication are entirely based on protein engineering and cellular synthesis.     

 

Resources

News & Media

香港科技大學開發新型「智能」蛋白質水凝膠

2017-07-10  科學  每日頭條  Read More

科大研水凝膠 可光感控藥物釋放

2017-07-27  社會新聞  hket  Read More

 

科大研發智能水凝膠 有望應用治療糖尿病

2017-07-28  教育  星島日報  Read More 

 

水凝膠遇光變液 助減胰島素注射 可載幹細胞修復器官

2017-07-28  港聞  明報  Read More

 

 

 

About us

SPES Tech is a research-intensive biotechnology startup with a mission to unveil next-generation therapeutics through advance in biomaterials. It is founded to provide cutting-edge hydrogel solutions for 3D and organoid culture for biomedical research to better understand the pathology of diseases. We also leverage the technology to develop a high-throughput cell screening system for pre-clinical evaluation of cell-based therapy.

 

CONTACT

For any general inquiries, please fill in the following contact form:

 
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